Synthesis of Protohypericin from Emodin

Authors

  • Dr. Dietrich Spitzner

    Corresponding author
    1. Institut für Chemie der Universität Hohenheim, Emil-Wolff-Strasse 14, D-7000 Stuttgart 70 (Germany)
    • Institut für Chemie der Universität Hohenheim, Emil-Wolff-Strasse 14, D-7000 Stuttgart 70 (Germany)
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  • Note added in proof (November 23, 1976): In the meantime D. W. Cameron et al., Aust. J. Chem. 29, 1509 (1976), reported similar results.

Abstract

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The violet plant pigment protohypericin(1) is formed in the dark by alkaline dimerization of emodin; it is transformed into hypericin by light and oxygen. 1H-NMR decoupling experiments establish the orientation of the two emodin units in (1)

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