Activation of Double Bonds in Dehydro Amino Acids: A Model for Pyridoxal-Containing Enzymes in Elimination-Addition Reactions

Authors

  • Prof. Dr. Ulrich Schmidt,

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    1. Organisch-Chemisches Institut der Universität Währinger Strasse 38, A-1090 Wien (Austria)
    • Organisch-Chemisches Institut der Universität Währinger Strasse 38, A-1090 Wien (Austria)
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  • Mag. Erhard Prantz

    1. Organisch-Chemisches Institut der Universität Währinger Strasse 38, A-1090 Wien (Austria)
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  • Dehydro Amino Acids, Part 10. This work was supported by the Fonds zur Förderung der wissenschaftlichen Forschung in Österreich.—Part 9: ref. [1].—Also: Amino Acids and Peptides, Part 23.—Part 22: ref [1].

Abstract

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Schiff bases of type (1) are models for pyridoxal-containing enzymes. The outstanding ability of compounds (1) to undergo addition can be demonstrated with phenylmethanethiol.

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