Functional Vinyl Carbanions—Deprotonation of β-(1-Pyrrolidinyl)acrylonitrile

Authors

  • Prof. Dr. Richard R. Schmidt,

    Corresponding author
    1. Fachbereich Chemie der Universität, Postfach 7733, D-7750 Konstanz (Germany)
    • Fachbereich Chemie der Universität, Postfach 7733, D-7750 Konstanz (Germany)
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  • Dipl.-Chem. Jörg Talbiersky

    1. Institut für Organische Chemie der Universität, Pfaffenwaldring 55, D-7000 Stuttgart 80 (Germany)
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  • Vinyl Anions, Part 4. This work was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie.—Part 3: R. R. Schmidt, B. Schmid, Tetrahedron Lett. 1977, 3583.

Abstract

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Selective electrophilic reactions at the α- or β-position of β-(1-pyrrolidinyl)acrylonitrile (1), NR2 = pyrrolidinyl, can be accomplished in many cases by lithiation of (1) at −113 or −76°C and subsequent reaction with the electrophile.

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