Advertisement

Asymmetric Synthesis of 2-Alkylcyclohexanones on Solid Phases

Authors


  • This work was supported by the National Research Council of Canada and York University.

Abstract

original image

Asymmetric syntheses on a kind of “Synthetic enzyme” appear highly promising, as shown by the reaction sequence illustrated below: (S)-2-methyl-and (S)-2-propycyclohexanone have each been obtained in 80% chemical yield and 95 and 60% optical yield, respectively. The chiral reagent (1) can be re-used.

Ancillary