Advertisement

Facile, Highly Selective Synthesis of α- and β-Disaccharides from 1-O-Metalated D-Ribofuranoses

Authors

  • Prof. Dr. Richard R. Schmidt,

    Corresponding author
    1. Fachbereich Chemie der Universität, Postfach 7733, D-7750 Konstanz (Germany)
    • Fachbereich Chemie der Universität, Postfach 7733, D-7750 Konstanz (Germany)
    Search for more papers by this author
  • Dipl.-Chem. Manfred Reichrath

    1. Fachbereich Chemie der Universität, Postfach 7733, D-7750 Konstanz (Germany)
    Search for more papers by this author

  • This work was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie.

  • Dedicated to Professor Hellmut Bredereck on the occasion of his 75th birthday

Abstract

original image

α- and β-Disaccharide syntheses not requiring halogenoses and heavy metals have many advantages. Depending on the nature and size of the 5-O-substituent R, compound (1) is metalated to give (2) (R [DOUBLE BOND] H) or (3) (R [DOUBLE BOND] CPh3, tBuMe2Si); (2) is a precursor of β-, and (3) a precursor of α-disaccharides

Ancillary