This work was supported by the Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Project 2.467.0.75 and 2.693.0.76).
New Evidence for Zwitterionic Intermediates in the Wittig Reaction†
Article first published online: 22 DEC 2003
Copyright © 1979 by Verlag Chemie, GmbH, Germany
Angewandte Chemie International Edition in English
Volume 18, Issue 8, pages 633–634, August 1979
How to Cite
Schlosser, M. and Tuong, H. B. (1979), New Evidence for Zwitterionic Intermediates in the Wittig Reaction. Angew. Chem. Int. Ed. Engl., 18: 633–634. doi: 10.1002/anie.197906331
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Received: 6 JUN 1979
The course of the Wittig reaction is still a topic of controversy; oxaphosphetanes (2) have been confirmed, betaines (1) not ruled out. Reaction of Ph3P⊕ C⊖(Me) CD2OLi with CH2O and that of the non-deuterated compound with CD2O lead to the same mixture of deuterated allyl alcohols. This result indicates an equilibrium between the different oxaphosphetans, i.e. the existence of a zwitterion.