Synthesis and Structure of 3-Chloro-4-hydroxy- and 3,4-epoxyphospholane 1-Oxides

Authors

  • Dr. Friedrich Cavagna,

    1. Hauptlaboratorium, Hoechst Aktiengesellschaft, D-6230 Frankfurt am Main 80 (Germany)
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  • Dr. Utz-Hellmuth Felcht,

    Corresponding author
    1. Hauptlaboratorium, Hoechst Aktiengesellschaft, D-6230 Frankfurt am Main 80 (Germany)
    • Hauptlaboratorium, Hoechst Aktiengesellschaft, D-6230 Frankfurt am Main 80 (Germany)
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  • Dr. Erich F. Paulus

    Corresponding author
    1. Hauptlaboratorium, Hoechst Aktiengesellschaft, D-6230 Frankfurt am Main 80 (Germany)
    • Hauptlaboratorium, Hoechst Aktiengesellschaft, D-6230 Frankfurt am Main 80 (Germany)
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  • Dedicated to Professor Rolf Sammet on the occasion of his 60th birthday

Abstract

original image

Epoxidation of phospholene oxides(1) to give (2) proceeds almost quantitatively by the route shown below, thus superseding previous methods. There is no need to isolate the intermediate (2). An X-ray structure analysis has been performed on one of the stereoisomers of (2a), R1 = OCH3, R2 = R3 = CH3.

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