The Chemistry of Hexahydroporphyrins, Part 3. This work was supported by the Swiss National Science Foundation. P. N. (postdoctoral fellow at the ETH 1977/1978) gratefully acknowledges a scholarship from the German Science Foundation.—Part 2: [1b].
Synthesis and Transformations of 5-Cyano-2,2,8,8,12,13,17,18-octamethylisobacteriochlorin†
Article first published online: 22 DEC 2003
Copyright © 1980 by Verlag Chemie, GmbH, Germany
Angewandte Chemie International Edition in English
Volume 19, Issue 2, pages 143–145, February 1980
How to Cite
Naab, P., Lattmann, R., Angst, C. and Eschenmoser, A. (1980), Synthesis and Transformations of 5-Cyano-2,2,8,8,12,13,17,18-octamethylisobacteriochlorin. Angew. Chem. Int. Ed. Engl., 19: 143–145. doi: 10.1002/anie.198001431
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Received: 29 OCT 1979
A model substrate for studies in the hexahydroporphyrin series, i.e. the title compound (1) having C2v symmetry, has been prepared by a multistep de-novo synthesis from a cyanosubstituted thiolactam. Catalytic hydrogenation of (1) affords the highly O2-sensitive 2,3,7,8,15,24-hexahydro derivative; attempts to incorporate metal ions into this species lead to complexes of the 1,2,3,7,8,20-hexahydro isomer.