Enantioselective Synthesis of ( R)-α-Vinylamino Acids

Authors

  • Prof. Dr. Ulrich Schöllkopf,

    Corresponding author
    1. Organisch-chemisches Institut der Universität, Tammannstrasse 2, D-3400 Göttingen (Germany)
    • Organisch-chemisches Institut der Universität Tammannstrasse 2, D-3400 Göttingen (Germany)
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  • Dipl.-Chem. Ulrich Groth

    1. Organisch-chemisches Institut der Universität, Tammannstrasse 2, D-3400 Göttingen (Germany)
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  • Asymmetric Synthesis via Heterocyclic Intermediates. Part 9.—Part 8: [4].

  • Dedicated to Professor Werner Reif on the occasion of his 60th birthday

Abstract

original image

Important enzyme inhibitors such as α-vinylamino acids (2) can be prepared in highly optically pure form in a few steps from the heterocycle cyclo(L-Val-Gly)(1) by the bislactim ether method.

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