Chemical Applications of NMR Isotope Effects: Ring Inversion and Conformational Equilibrium in [2H1]Cyclohexane

Authors

  • Dipl.-Chem. Rafet Aydin,

    1. Universität–Gesamthochschule. FB 8, OC II, Postfach 210209, D-5900 Siegen 21 (Germany)
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  • Prof. Dr. Harold Günther

    Corresponding author
    1. Universität–Gesamthochschule. FB 8, OC II, Postfach 210209, D-5900 Siegen 21 (Germany)
    • Universität–Gesamthochschule. FB 8, OC II, Postfach 210209, D-5900 Siegen 21 (Germany)
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  • This work was supported by the Deutsche Forechungsgemeinschaft and by the Fonds der Chemischen Industrie. We are indebted to Dr. J. R. Everett for helpful comments.

Abstract

original image

The large and easily measurable 1H/2H isotope effect on the chemical shift of the 13C nucleus has been exploited in the investigation of the ring inversion (1a)⇌(1b). At equilibrium, (1a) predominates.

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