For many of the new amino acids a collective reference, or one to the most recent synthetic work, is given when possible.
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Review
Article first published online: 22 DEC 2003
DOI: 10.1002/anie.198308161
Copyright © 1983 by Verlag Chemie, GmbH, Germany
Issue
Angewandte Chemie International Edition in English
Volume 22, Issue 11, pages 816–828, November 1983
Additional Information
How to Cite
Wagner, I. and Musso, H. (1983), New Naturally Occurring Amino Acids. Angew. Chem. Int. Ed. Engl., 22: 816–828. doi: 10.1002/anie.198308161
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Dedicated to Professor Hans Brockman on the occasion of his 80th birthday
Publication History
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Received: 29 JUN 1983
- Abstract
- References
- Cited By
Keywords:
- Amino acids;
- Natural products
Abstract
The majority of the 500 or so naturally occurring amino acids known today were discovered during the last 30 years, for example during the search for new antibiotics in the culture media of microorganisms, or as components of the antibiotics in fungi, seeds, in numerous plants and fruits, and in the body fluids of animals. Some 240 of these amino acids occur free in nature, some only as intermediates in metabolism. This article provides an overview of the developments that have taken place in this area since 1956 when the last review appeared. Summary accounts are presented, dealing with new unsaturated amino acids, cyclopropane- and cyclobutane-amino acids, heterocyclic amino acids, halogen-containing amino acids sulfur-, selenium- and phosphorus-containing amino acids as well as aliphatic amino acids. In a few cases, e. g. betalamic acid and muscaflavin, the biosynthesis is described in detail.