This work was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie. We thank Fa. Raschig, Ludwigshafen, for supplying the acetylpyridines.
Optically Active α-Arylcarboxylic Acids by Kinetic Resolution: Pyrethroid Acids†
Article first published online: 22 DEC 2003
Copyright © 1984 by Verlag Chemie, GmbH, Germany
Angewandte Chemie International Edition in English
Volume 23, Issue 2, pages 162–164, February 1984
How to Cite
Rüchardt, C., Gärtner, H. and Salz, U. (1984), Optically Active α-Arylcarboxylic Acids by Kinetic Resolution: Pyrethroid Acids. Angew. Chem. Int. Ed. Engl., 23: 162–164. doi: 10.1002/anie.198401621
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Revised: 28 NOV 1983
- Manuscript Received: 17 OCT 1983
By means of the chiral auxiliaries 1-m- and 1-p-pyridylethanols 2, racemic α-arylcarboxylic acids (as anhydrides 1) can be resolved into their enantiomers. One enantiomer accumulates in the ester 3 and the other in the acid 4. Interesting examples are 2-aryl-3-methylbutyric acids (pyrethroid acids).