This work was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie. The results of this communication were delivered in part in a lecture at the 193rd ACS Meeting in Denver, CO (USA), Spring 1987.
Host-Guest Bonding of Oxoanions to Guanidinium Anchor Groups†
Article first published online: 22 DEC 2003
Copyright © 1988 by VCH Verlagsgesellschaft mbH, Germany
Angewandte Chemie International Edition in English
Volume 27, Issue 11, pages 1516–1518, November 1988
How to Cite
Müller, G., Riede, J. and Schmidtchen, F. P. (1988), Host-Guest Bonding of Oxoanions to Guanidinium Anchor Groups. Angew. Chem. Int. Ed. Engl., 27: 1516–1518. doi: 10.1002/anie.198815161
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Received: 30 MAY 1988
Adaptation of the recognition principle of many biogenic receptors, which make use of the interaction between the guanidinium function of arginyl side chains with carboxylate and phosphate groups of substrates, was used to design and synthesize new host compounds. The bicyclic guanidinium compounds (1, shown schematically) bind p-nitrobenzoate (NMR-titration) and acetate (X-ray structural analysis).