Copyright © The Nobel Foundation 1989. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.
Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism (Nobel Lecture)†
Article first published online: 30 DEC 2003
Copyright © 1989 by VCH Verlagsgesellschaft mbH, Germany
Angewandte Chemie International Edition in English
Volume 28, Issue 7, pages 886–894, July 1989
How to Cite
Black, J. W. (1989), Drugs from Emasculated Hormones: The Principle of Syntopic Antagonism (Nobel Lecture). Angew. Chem. Int. Ed. Engl., 28: 886–894. doi: 10.1002/anie.198908861
- Issue published online: 30 DEC 2003
- Article first published online: 30 DEC 2003
- Manuscript Received: 27 JAN 1989
- Drug research;
- Syntopic antagonism;
- Nobel lecture;
- Hormone antagonists
Hormones as prototypes in the development of drugs; this was the theme of the lecture by the third recipient of the 1988 Nobel Prize in Medicine, whose research led to compounds such as propranolol 1, derived from adrenaline andused as a drug against angina pectoris illnesses, and burimamide 2, derived from histamine, used against increased gastric secretion, the cause of stomach and duodenal ulcers.