In memory of Franz Sondheimer
Article first published online: 22 DEC 2003
Copyright © 1993 by VCH Verlagsgesellschaft mbH, Germany
Angewandte Chemie International Edition in English
Volume 32, Issue 10, pages 1377–1385, October 1993
How to Cite
Nicolaou, K. C. (1993), The Battle of Calicheamicin γ. Angew. Chem. Int. Ed. Engl., 32: 1377–1385. doi: 10.1002/anie.199313773
Professor Franz Sondheimer was one of the most influential acetylene chemists of the 20th century and from whom the author learned his first acetylene chemistry while studying at University College, London, as a doctoral student jointly with him and P. J. Garratt.
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Manuscript Received: 12 MAY 1993
- Natural products;
- Total synthesis
The first total synthesis of calicheamicin γ was achieved approximately a year ago. In this article, the author presents a personal account of the events, in chronological order, that led to this success story in total synthesis.