Reciprocal Template Effects in a Replication Cycle

Authors

  • Roland J. Pieters,

    1. Department of Chemistry, Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Telefax: Int. code + (617)253-7929
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  • Ivan Huc,

    1. Department of Chemistry, Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Telefax: Int. code + (617)253-7929
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  • Prof. Julius Rebek Jr.

    Corresponding author
    1. Department of Chemistry, Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Telefax: Int. code + (617)253-7929
    • Department of Chemistry, Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Telefax: Int. code + (617)253-7929
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  • This research was supported by the National Institutes of Health, the National Science Foundation, and Rhǒne-Poulenc (predoctoral fellowship to I. H).

Abstract

original image

Complementary surfaces and reactive functionalities are the ingredients of a system that mimics the two-step replication process of DNA. Two separate coupling reactions each give a product that is a template for the next reaction.

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