This work was supported by the DGICYT (project PB91-0612-C03-02). D. J. C. and C. M. acknowledge the receipt of predoctoral fellowships from the Ministerio de Educatión y Ciencia.
Synthesis of Oxa- and Azapalladacycles from Organostannanes†
Article first published online: 22 DEC 2003
Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany
Angewandte Chemie International Edition in English
Volume 33, Issue 23-24, pages 2445–2447, January 3, 1995
How to Cite
Cárdenas, D. J., Mateo, C. and Echavarren, A. M. (1995), Synthesis of Oxa- and Azapalladacycles from Organostannanes. Angew. Chem. Int. Ed. Engl., 33: 2445–2447. doi: 10.1002/anie.199424451
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
An intramolecular Pd–C coupling reaction yields the oxapalladacycle 1. This is the first time that the transmetalation intermediate in the Stille coupling reaction has been isolated. Complexes of type 1 react readily with alkyl, allyl, benzyl, and acyl halides to form aryl-carbon bonds. This reaction can be extended to the preparation of substituted derivatives of 1 and the aza analogue 2.