Sugar Calixarenes: Preparation of Calix[4]arenes Substituted at the Lower and Upper Rims with O-Glycosyl Groups

Authors

  • Dr. Alberto Marra,

    1. Dipartimento di Chimica, Universita di Ferrara Via L. Borsari 46, 1–44100 Ferrara (Italy) Telefax: Int. code + (532)240709
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  • Dr. Marie-Christine Scherrmann,

    1. Dipartimento di Chimica, Universita di Ferrara Via L. Borsari 46, 1–44100 Ferrara (Italy) Telefax: Int. code + (532)240709
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  • Prof. Alessandro Dondoni,

    Corresponding author
    1. Dipartimento di Chimica, Universita di Ferrara Via L. Borsari 46, 1–44100 Ferrara (Italy) Telefax: Int. code + (532)240709
    • Dipartimento di Chimica, Universita di Ferrara Via L. Borsari 46, 1-44100 Ferrara (Italy) Telefax: Int. code + (532)240709
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  • Prof. Rocco Ungaro,

    Corresponding author
    1. Dipartimento di Chimica Organica e Industriale, Università di Parma Viale delle Scienze, 1-43100 Parma (Italy) Telefax: Int. code + (521)905472
    • Dipartimento di Chimica Organica e Industriale, Universita di Parma Viale delle Scienze, 1-43100 Parma (Italy) Telefax: Int. code + (521)905472
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  • Dr. Alessandro Casnati,

    1. Dipartimento di Chimica Organica e Industriale, Università di Parma Viale delle Scienze, 1-43100 Parma (Italy) Telefax: Int. code + (521)905472
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  • Dr. Patrizia Minari

    1. Dipartimento di Chimica Organica e Industriale, Università di Parma Viale delle Scienze, 1-43100 Parma (Italy) Telefax: Int. code + (521)905472
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  • We thank Dr. M. Hamdan, Glaxo Research Center, Verona (Italy), for mass spectral determinations.

Abstract

original image

A chiral hydrophilic environment is created at either rim of calix[4]arene by the synthesis of glycosyl derivatives such as the water-soluble tetragalactosyl calixarene 1. This derivative is potentially an attractive synthetic receptor for chiral recognition of polar organic molecules.

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