Photoswitchable Electrical Communication of Glucose Oxidase and Glutathione Reductase with Electrode Surfaces through Photoisomerizable Redox Mediators

Authors

  • Mazzi Lion-Dagan,

    1. Institute of Chemistry The Hebrew University of Jerusalem Jerusalem 91904 (Israel) Telefax: Int. code + (2)6527715
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  • Sharon Marx-Tibbon,

    1. Institute of Chemistry The Hebrew University of Jerusalem Jerusalem 91904 (Israel) Telefax: Int. code + (2)6527715
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  • Dr. Eugenii Katz,

    1. Institute of Chemistry The Hebrew University of Jerusalem Jerusalem 91904 (Israel) Telefax: Int. code + (2)6527715
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  • Prof. Itamar Willner

    Corresponding author
    1. Institute of Chemistry The Hebrew University of Jerusalem Jerusalem 91904 (Israel) Telefax: Int. code + (2)6527715
    • Institute of Chemistry The Hebrew University of Jerusalem Jerusalem 91904 (Israel) Telefax: Int. code + (2)6527715
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  • This research was supported by the Ministry of Science and Technology, Israel, and by the Commission of the European Community.

Abstract

original image

Multiple layers of glucose oxidase (or glutathione reductase) on Au electrodes can be activated and deactivated reversibly by a ferrocene–nitrospiropyran (or a bipyridinium–nitrospiropyran) acting as a photoisomerizable electron relay. The anchoring of the first enzyme layer to the surface of the electrode is shown schematically below.

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