A New Application of Capillary Zone Electrophoresis: Determination of Energy Barriers of Configurationally Labile Chiral Compounds


  • C. W. thanks the Fonds der Chemischen Industrie for a scholarship.


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The direct determination of the rates of racemization of configurationally labile, chiral compounds like 1 is now possible with capillary zone electrophoresis. The method obviates the isolation of the enantiomers before the enantiomerization experiment, which is required in chiroptical methods, and the computer simulations necessary for dynamic procedures.