Tail-to-tail C,C-coupled pyranoses or furanoses like 2 with a disaccharide-like structure were obtained from hydroxylated dialdehydes like 1 under aldolase catalysis. The key step is the twofold addition of dihydroxyacetone phosphate. As many as six stereocenters in the products can be controlled by a thermodynamically selective reaction mode.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.