A Phycocyanobilin Seryliminoester as a New Model for the Chromophore–Protein Interaction in Phytochrome


  • This work was supported by the Fonds zur Förderung der wissenschaftlichen Forschung (project no. P-9166).

  • Dedicated to Professor Albert Eschenmoser on the occasion of his 70th birthday


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The new phytochrome model compound 1 is characterized by the covalent linkage of a serine side chain with the ring-A lactam of the phycocyanobilin chromophore. The model readily explains the absorption properties, ensures photoreversibility, and offers the possibility for thermal back reaction.