Rhodium-Catalyzed Hydroformylation of Internal Alkynes to α,β-Unsaturated Aldehydes


  • We thank Union Carbide for financial support. G.D.C. thanks the National Science Foundation for a graduate fellowship. S.L.B. acknowledges additional support as a Fellow of the Alfred P. Sloan Foundation and a Camille and Henry Dreyfus Teacher-Scholar.


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Under mild conditions—1 atm syngas and room temperature—symmetric internal alkynes are selectively converted into α,β-unsaturated aldehydes in good yields [Eq. (a)].