Solution and Solid-State Structure of a Lithiated Phosphane Oxide


  • We are grateful to the National Institutes of Health (GM 45532) for generous support of this research. We thank Dr. Vera Mainz for NMR technical assistance.


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The anionic benzyl carbon atom is sp2 hybridized in 1, the first lithiated phosphane oxide that has been characterized by X-ray crystallography. In the solid state as well as in THF solution, 1 is shown to exist as a dimer with no Li[BOND]C contacts. Unlike related phosphonamides, 1 prefers an orthogonal conformation of the benzylic group in the solid state.