The Catalyst Precursor, Catalyst, and Intermediate in the RuII-Promoted Asymmetric Hydrogen Transfer between Alcohols and Ketones

Authors

  • Dr. Karl-Josef Haack,

    1. ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
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  • Dr. Shohei Hashiguchi,

    1. ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
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  • Dr. Akio Fujii,

    1. ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
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  • Dr. Takao Ikariya,

    1. ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
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  • Prof. Dr. Ryoji Noyori

    Corresponding author
    1. ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
    Current affiliation:
    1. Department of Chemistry, Nagoya University Chikusa, Nagoya 464-01 (Japan), Fax: Int. code + (52) 783-4177
    • ERATO Molecular Catalysis Project Research Development Corporation of Japan 1247 Yachigusa, Yakusa-cho, Toyota 470-03 (Japan) Fax: Int. code + (565)48-4909
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  • The authors are grateful to Professor Masashi Yamakawa of Kinjo Gakuin University, Dr. Philip Jessop, and Kazuhiko Matsumura for valuable discussions. Thanks are also due to Mieko Kunieda of the Research Development Corporation of Japan for skillful analytical assistance.

Abstract

original image

New insight into the mechanism of catalysis. The purple 16-electron complex 1 and the yellow 18-electron complex 2 directly mediate the asymmetric, RuII-catalyzed hydrogen transfer between secondary alcohols and ketones. Both complexes were characterized by X-ray crystallography.

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