Get access

Self-Assembled Monolayers That Transduce Enzymatic Activities to Electrical Signals


  • This work was supported by the National Science Foundation and the Materials Research Science and Engineering Center.


original image

A dynamic substrate that transduces a biological activity into an electrical signal has been developed (see scheme). The enzymatic conversion of a redox-inactive substrate presented at a self-assembled monolayer produced a redox-active product that is monitored electrochemically in real time.