This research was supported by the National Science Foundation (CHE-0131944). Fellowship support from the Stanford Graduate Fellowship (G.G.G.) is gratefully acknowledged.
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Communication
The Dienyl Pauson–Khand Reaction†
Article first published online: 23 APR 2003
DOI: 10.1002/anie.200350949
© 2002 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Wender, P. A., Deschamps, N. M. and Gamber, G. G. (2003), The Dienyl Pauson–Khand Reaction. Angew. Chem. Int. Ed., 42: 1853–1857. doi: 10.1002/anie.200350949
- †
Publication History
- Issue published online: 23 APR 2003
- Article first published online: 23 APR 2003
- Manuscript Received: 16 JAN 2003
Keywords:
- cycloaddition;
- dienes;
- homogeneous catalysis;
- Pauson–Khand reaction;
- rhodium
The diene plays a key role in the Pauson–Khand [2+2+1] reaction of tethered dienynes (see scheme). These reactions are accelerated by the diene (relative to an alkene) and proceed in good to excellent yields, often at room temperature, in the presence of carbon monoxide, [RhCl(CO)(PPh3)2], and AgSbF6.