This research was supported by the National Science Foundation (CHE-0131944). Fellowship support from the Stanford Graduate Fellowship (G.G.G.) is gratefully acknowledged.
The Dienyl Pauson–Khand Reaction†
Article first published online: 23 APR 2003
© 2002 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 42, Issue 16, pages 1853–1857, April 25, 2003
How to Cite
Wender, P. A., Deschamps, N. M. and Gamber, G. G. (2003), The Dienyl Pauson–Khand Reaction. Angew. Chem. Int. Ed., 42: 1853–1857. doi: 10.1002/anie.200350949
- Issue published online: 23 APR 2003
- Article first published online: 23 APR 2003
- Manuscript Received: 16 JAN 2003
- homogeneous catalysis;
- Pauson–Khand reaction;
The diene plays a key role in the Pauson–Khand [2+2+1] reaction of tethered dienynes (see scheme). These reactions are accelerated by the diene (relative to an alkene) and proceed in good to excellent yields, often at room temperature, in the presence of carbon monoxide, [RhCl(CO)(PPh3)2], and AgSbF6.