This work was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan. We thank the technical staff in the Materials Analysis Center of ISIR, Osaka University.
Metal-Bridged Polymers as Insoluble Multicomponent Asymmetric Catalysts with High Enantiocontrol: An Approach for the Immobilization of Catalysts without Using any Support†
Article first published online: 25 NOV 2003
Copyright © 2003 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 42, Issue 46, pages 5711–5714, December 1, 2003
How to Cite
Takizawa, S., Somei, H., Jayaprakash, D. and Sasai, H. (2003), Metal-Bridged Polymers as Insoluble Multicomponent Asymmetric Catalysts with High Enantiocontrol: An Approach for the Immobilization of Catalysts without Using any Support. Angew. Chem. Int. Ed., 42: 5711–5714. doi: 10.1002/anie.200352354
- Issue published online: 25 NOV 2003
- Article first published online: 25 NOV 2003
- Manuscript Revised: 18 AUG 2003
- Manuscript Received: 11 JUL 2003
- asymmetric catalysis;
- heterogeneous catalysis;
- synthetic methods
Immobile without support: The first synthesis of chiral Al-bridged and Ti-bridged polymers by a metal-mediated self-assembly of (R,R)-6,6′-bi(binol) (binol=1,1′-bi-2-naphthol), which bears two pairs of phenolic hydroxy groups at the opposite sides in the molecule, is described (see scheme, X=OH or O). The polymers are found to promote asymmetric Michael reaction and carbonyl–ene reaction with high enantioselectivity and can be reused.