B.L. and H.K. acknowledge the Fonds der Chemischen Industrie and the DFG (Emmy-Noether-fellowships LU 835/1-1, KC 147/35) for financial support. We thank Prof. Dr.-Ing O. Nuyken, Dr. R. Jordan, Dr. M. Zweckstetter, Dr. R. Marx, O. Hiltner, and W. Günther for their help.
An Easy and Scalable Method for the Partial Alignment of Organic Molecules for Measuring Residual Dipolar Couplings†
Article first published online: 18 FEB 2004
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 43, Issue 9, pages 1092–1094, February 20, 2004
How to Cite
Luy, B., Kobzar, K. and Kessler, H. (2004), An Easy and Scalable Method for the Partial Alignment of Organic Molecules for Measuring Residual Dipolar Couplings. Angew. Chem. Int. Ed., 43: 1092–1094. doi: 10.1002/anie.200352860
- Issue published online: 18 FEB 2004
- Article first published online: 18 FEB 2004
- Manuscript Received: 12 SEP 2003
- NMR spectroscopy;
- partial alignment;
- residual dipolar coupling
Stretched polystyrene gel (see picture) induces partial alignment of small molecules in an organic solvent for the measurement of residual dipolar couplings in high-resolution NMR spectroscopy. The degree of orientation can be varied over a wide range by the amount of cross-linking of the polymer. An important NMR parameter can thus be measured routinely.