This research was supported by DARPA/NSF (ECS-0004030) and NIH (GM 65364), and used the MRSEC shared facilities supported by the NSF under Award No. DMR-9809363. V.L. was a recipient of a postdoctoral fellowship from the Swiss National Science Foundation. A.S. was a recipient of a Howard Hughes Medical Institute Predoctoral Fellowship. We thank Tyler Aldredge of the Center for Genomics Research for technical assistance.
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Communication
An Integrated Approach to a Portable and Low-Cost Immunoassay for Resource-Poor Settings†
Article first published online: 14 JAN 2004
DOI: 10.1002/anie.200353016
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Sia, S. K., Linder, V., Parviz, B. A., Siegel, A. and Whitesides, G. M. (2004), An Integrated Approach to a Portable and Low-Cost Immunoassay for Resource-Poor Settings. Angew. Chem. Int. Ed., 43: 498–502. doi: 10.1002/anie.200353016
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Publication History
- Issue published online: 14 JAN 2004
- Article first published online: 14 JAN 2004
- Manuscript Received: 6 OCT 2003
Keywords:
- analytical methods;
- colloids;
- immunoassays;
- microfluidics;
- proteins
An integrated approach for detecting proteins that is low-cost, portable, battery-operated, and works under field conditions such as direct sunlight has been developed. The “POCKET immunoassay” uses commercially available components, and exhibits an analytical performance approaching that of established bench-top techniques. It may be appropriate for the diagnosis of infectious diseases, such as HIV/AIDS, in developing countries (see picture).