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An Integrated Approach to a Portable and Low-Cost Immunoassay for Resource-Poor Settings

Authors


  • This research was supported by DARPA/NSF (ECS-0004030) and NIH (GM 65364), and used the MRSEC shared facilities supported by the NSF under Award No. DMR-9809363. V.L. was a recipient of a postdoctoral fellowship from the Swiss National Science Foundation. A.S. was a recipient of a Howard Hughes Medical Institute Predoctoral Fellowship. We thank Tyler Aldredge of the Center for Genomics Research for technical assistance.

Abstract

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An integrated approach for detecting proteins that is low-cost, portable, battery-operated, and works under field conditions such as direct sunlight has been developed. The “POCKET immunoassay” uses commercially available components, and exhibits an analytical performance approaching that of established bench-top techniques. It may be appropriate for the diagnosis of infectious diseases, such as HIV/AIDS, in developing countries (see picture).

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