This work was supported by DARPA under grant F30602-00-2-0567, the Department of Energy under grants DE FG02 88ER13949 and DE FG02 99ER62797 and the National Institutes of Allergies and Infectious Diseases under the Great Lakes Regional Center for Excellence. The authors thank G. Fried and K. Garsha for assistance with confocal microscopy and for discussions.
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Communication
Nanocapillary Arrays Effect Mixing and Reaction in Multilayer Fluidic Structures†
Article first published online: 24 MAR 2004
DOI: 10.1002/anie.200353279
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Kuo, T.-C., Kim, H.-K., Cannon, D. M., Shannon, M. A., Sweedler, J. V. and Bohn, P. W. (2004), Nanocapillary Arrays Effect Mixing and Reaction in Multilayer Fluidic Structures. Angew. Chem. Int. Ed., 43: 1862–1865. doi: 10.1002/anie.200353279
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Publication History
- Issue published online: 24 MAR 2004
- Article first published online: 24 MAR 2004
- Manuscript Revised: 18 DEC 2003
- Manuscript Received: 7 NOV 2003
Keywords:
- fluorescent probes;
- kinetics;
- microreactors;
- nanostructures;
- sensors
Reactant mixing is implemented in structures with characteristic length scales of nanometers (see picture). Mixing occurs within micron distances rather than the centimeters that are often needed for laminar microflows. The application of the nanocapillary mixer to detect Ca2+ ions demonstrates its potential use in sensors.