This work was supported by the Deutsche Forschungsgemeinschaft (Leibniz program) and the Fonds der Chemischen Industrie.
A Catalytic Approach to (R)-(+)-Muscopyridine with Integrated “Self-Clearance”†
Article first published online: 20 JAN 2003
© 2002 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 42, Issue 3, pages 308–311, January 20, 2003
How to Cite
Fürstner, A. and Leitner, A. (2003), A Catalytic Approach to (R)-(+)-Muscopyridine with Integrated “Self-Clearance”. Angew. Chem. Int. Ed., 42: 308–311. doi: 10.1002/anie.200390103
- Issue published online: 20 JAN 2003
- Article first published online: 20 JAN 2003
- Manuscript Revised: 29 OCT 2002
- Manuscript Received: 6 SEP 2002
The integration of various metal-catalyzed reactions into a one-pot processes opens an unprecedentedly short and efficient route to the odoriferous alkaloid (R)-(+)-muscopyridine. Importantly, it is shown how metathesis can be used for a most convenient “self-clearance” of a product mixture (see scheme; OTf=CF3SO3).