We thank Dr. T. Ikoma (National Institute for Materials Science, Biomaterials Center, Tsukuba, Japan), Dr. D. Scott, Mrs G. Shaw and Dr. A. M. Seddon (University of Bristol) for help with CD spectroscopy, AUC, mass spectroscopy, and enzyme kinetics, respectively. The EPSRC (UK), Max Planck Society, and University of Bristol (ORS award to A.J.P.) are acknowledged for their financial support.
Synthesis and Self-Assembly of Organoclay-Wrapped Biomolecules†
Article first published online: 16 SEP 2004
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 43, Issue 37, pages 4928–4933, September 20, 2004
How to Cite
Patil, A. J., Muthusamy, E. and Mann, S. (2004), Synthesis and Self-Assembly of Organoclay-Wrapped Biomolecules. Angew. Chem. Int. Ed., 43: 4928–4933. doi: 10.1002/anie.200453868
- Issue published online: 16 SEP 2004
- Article first published online: 16 SEP 2004
- Manuscript Revised: 26 APR 2004
- Manuscript Received: 27 JAN 2004
- biological activity;
- organic-inorganic hybrid composites;
Gift wrapped: Biomolecules can be enveloped within an ultrathin shell of an aminopropyl-functionalized magnesium (organo)phyllosilicate to produce aqueous dispersions of discrete protein–inorganic nanoparticles. Similar procedures but with organoclay oligomers that have pendent long-chain hydrophobic moieties result in self-assembly of the protein–inorganic nanoparticles into higher-order superstructures (see picture).