Organic Protein Chemistry: Drug Discovery through the Chemical Modification of Proteins

Authors

  • Jörg Rademann Prof. Dr.

    1. FMP Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Strasse 10, 13125 Berlin, Germany, and, Institut für Chemie, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany, Fax: (+49) 30-94793-159
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Abstract

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Recent strategies used in the hunt for new active compounds employ chemically modified proteins that are formed by ligation techniques and then transformed chemically. The modified proteins have been successful both as active compounds and in the search for new ligands and binding pockets.

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