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Keywords:

  • aromatic substitution;
  • glycolipids;
  • lipid analogues;
  • nitrogen fixation;
  • oligosaccharides
Thumbnail image of graphical abstract

A “Nod” in the right direction: Aromatic analogues of the lipooligosaccharidic nodulation (Nod) factors involved in the symbiosis of Sinorhizobium meliloti and legumes are easily assembled from very simple precursors by combining biotechnological and chemical procedures. Some of these analogues (see structure) bind tightly to a specific binding protein and form a new class of glycolipid mimics.