We thank the EPSRC and the University of Huddersfield for financial support.
Allosteric and Electrostatic Reprogramming of a Ditopic Ligand†
Article first published online: 25 AUG 2004
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 43, Issue 34, pages 4515–4518, August 27, 2004
How to Cite
Baylies, C. J., Harding, L. P., Jeffery, J. C., Riis-Johannessen, T. and Rice, C. R. (2004), Allosteric and Electrostatic Reprogramming of a Ditopic Ligand. Angew. Chem. Int. Ed., 43: 4515–4518. doi: 10.1002/anie.200460424
- Issue published online: 25 AUG 2004
- Article first published online: 25 AUG 2004
- Manuscript Received: 23 APR 2004
- helical structures;
- N ligands
A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl-thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).