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Difluoromethyl Phenyl Sulfone, a Difluoromethylidene Equivalent: Use in the Synthesis of 1,1-Difluoro-1-alkenes

Authors

  • G. K. Surya Prakash Prof. Dr.,

    1. Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA, Fax: (+1) 213-740-6270
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  • Jinbo Hu Dr.,

    1. Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA, Fax: (+1) 213-740-6270
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  • Ying Wang,

    1. Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA, Fax: (+1) 213-740-6270
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  • George A. Olah Prof. Dr.

    1. Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California, University Park, Los Angeles, CA 90089-1661, USA, Fax: (+1) 213-740-6270
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  • Support of our work by Loker Hydrocarbon Research Institute is gratefully acknowledged.

Abstract

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A nucleophilic substitution–elimination reaction strategy in which difluoromethyl phenyl sulfone is used as a selective difluoromethylidene equivalent allows the facile synthesis of 1,1-difluoro-1-alkenes from primary alkyl halides (see scheme).

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