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Are β-Acylaminoacrylates Hydrogenated in the Same Way as α-Acylaminoacrylates?


  • We thank the Deutsche Forschungsgemeinschaft for their generous support as well as Prof. C. R. Landis for stimulating discussions. We especially thank C. Pribbenow for skilled technical assistance.


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Five catalyst–substrate complexes of the type [Rh(chiral ligand)(β-dehydroamino acid derivative)]BF4 were characterized for the first time by X-ray analysis (see example). Low-temperature NMR spectroscopy proved that three of these complexes are “major” substrate complexes, which lead to the main product in asymmetric hydrogenation, contrary to the known classical examples with analogous α-dehydroamino acid derivatives.