This work was supported by the Deutsche Forschungsgemeinschaft, the Fonds der Chemischen Industrie, and the Dr. Otto Röhm Gedächtnisstiftung, Darmstadt. We thank Professor E. Winterfeldt for his generous support of our research.
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Communication
Hydroamination/Hydrosilylation Sequence Catalyzed by Titanium Complexes†
Article first published online: 8 APR 2005
DOI: 10.1002/anie.200462250
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Heutling, A., Pohlki, F., Bytschkov, I. and Doye, S. (2005), Hydroamination/Hydrosilylation Sequence Catalyzed by Titanium Complexes. Angewandte Chemie International Edition, 44: 2951–2954. doi: 10.1002/anie.200462250
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Publication History
- Issue published online: 3 MAY 2005
- Article first published online: 8 APR 2005
- Manuscript Received: 8 OCT 2004
Keywords:
- alkynes;
- amines;
- hydroamination;
- hydrosilylation;
- titanium
Graphical Abstract
A single precatalyst is used for the sequential combination of the Ti-catalyzed hydroamination of alkynes with the Ti-catalyzed hydrosilylation of imines. In this way alkynes and primary amines are converted efficiently into secondary amines in a fully catalytic one-pot process (see scheme).