This Highlight was written to coincide with the awarding of the 2004 Nobel Prize in Medicine and is dedicated to Prof. Dr. R. Luft, initiator of research on odorants in the late 1960s at the Université de Nice-Sophia Antipolis.
Highlight
The Molecular Basis of Olfactory Chemoreception†
Article first published online: 1 DEC 2004
DOI: 10.1002/anie.200462322
Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Meierhenrich, U. J., Golebiowski, J., Fernandez, X. and Cabrol-Bass, D. (2004), The Molecular Basis of Olfactory Chemoreception. Angewandte Chemie International Edition, 43: 6410–6412. doi: 10.1002/anie.200462322
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Publication History
- Issue published online: 1 DEC 2004
- Article first published online: 1 DEC 2004
- Abstract
- Article
- References
- Cited By
Keywords:
- bioorganic chemistry;
- fragrances;
- gene expression;
- protein models;
- protein structures
Graphical Abstract

The Nobel Price in Medicine this year went to Richard Axel and Linda Buck, who elucidated the molecular basis of the olfactory reception of fragrances and the neuronal preprocessing of information in the olfactory system. From the viewpoint of a chemist, these studies offer fascinating perspectives. For example, they enable an understanding of the perception of odors by transmembrane proteins (see picture).

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