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Keywords:

  • DNA adduct;
  • DNA damage;
  • DNA methylation;
  • electrophoresis;
  • laser-induced fluorescence detection

It was reported that 1,N6-etheno-2′-deoxyadenosine-3′-monophosphate (etheno-dAMP) elutes before 2′-deoxyadenosine-3′-monophosphate (dAMP). The authors have now found that etheno-dAMP elutes immediately after 2′-deoxythymidine-3′-monophosphate (dTMP). The assignment of the signals in the Communication relied on a commercially modified oligonucleotide standard thought to contain etheno-dAMP. As the synthesized 1,N6-etheno-2′-deoxyadenosine-3′-monophosphates are now characterized unambiguously, the mistake must have been because of an improperly defined oligonucleotide standard or decomposition of the modified oligonucleotide. The authors apologize for the error.

  • 1
    Angew. Chem. Int. Ed. 2002, 41, 445–448, DOI: 10.1002/1521-3773(20020201)41:3<445::AID-ANIE445>3.0.CO;2-7