Quantitative Spatial Mapping of Mixing in Microfluidic Systems

Authors

  • Steven W. Magennis Dr.,

    1. Collaborative Optical Spectroscopy, Micromanipulation and Imaging Centre (COSMIC) and the School of Chemistry, The University of Edinburgh, King's Buildings, Edinburgh EH9 3JZ, UK, Fax: (+44) 131-650-4743
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  • Emmelyn M. Graham,

    1. Collaborative Optical Spectroscopy, Micromanipulation and Imaging Centre (COSMIC) and the School of Chemistry, The University of Edinburgh, King's Buildings, Edinburgh EH9 3JZ, UK, Fax: (+44) 131-650-4743
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  • Anita C. Jones Dr.

    1. Collaborative Optical Spectroscopy, Micromanipulation and Imaging Centre (COSMIC) and the School of Chemistry, The University of Edinburgh, King's Buildings, Edinburgh EH9 3JZ, UK, Fax: (+44) 131-650-4743
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  • This work was supported by the EPSRC Insight Faraday Partnership, SHEFC and Lab 901 Ltd. We thank Andy Garrie for fabricating the flow cell, and Dave Towers and Ken Macnamara for helpful discussions.

Abstract

original image

The problem of miniaturizing the mixing process is a barrier to the advance of microfluidic technology. Fluorescence lifetime imaging is a powerful technique for the quantitative mapping of mixing in microfluidic systems, providing information essential to the design and evaluation of next-generation devices. With the use of a pulsed laser (B), mixing in a microfluidic cell (A) can be measured with fluorescence (C); a sample image is shown (right).

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