This work was supported by a Grant-in-Aid for Scientific Research for Young Scientists (A) (No. 15 685 006) to Y.N. from the Ministry of Education, Culture, Sports, Science, and Technology, Japan.
Asymmetric Carboselenenylation Reaction of Alkenes with Aromatic Compounds†
Article first published online: 4 MAY 2005
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Angewandte Chemie International Edition
Volume 44, Issue 23, pages 3588–3591, June 6, 2005
How to Cite
Okamoto, K., Nishibayashi, Y., Uemura, S. and Toshimitsu, A. (2005), Asymmetric Carboselenenylation Reaction of Alkenes with Aromatic Compounds. Angew. Chem. Int. Ed., 44: 3588–3591. doi: 10.1002/anie.200500573
- Issue published online: 30 MAY 2005
- Article first published online: 4 MAY 2005
- Manuscript Received: 16 FEB 2005
- asymmetric synthesis;
- synthetic methods
High diastereoselectivity is attained in the carboselenenylation reaction of simple alkenes with aromatic compounds by using a C2-symmetric areneselenenyl triflate (see scheme). This asymmetric Friedel–Crafts-type reaction is a convenient procedure for the preparation of chiral hydrocarbons bearing an aryl moiety at the stereogenic carbon atom. Tf=trifluoromethanesulfonyl; M.S.=molecular sieves.