This work was supported by the National Basic Research Program of China (No. 2003CB415001), the National Natural Science Foundation of China (No. 20475028, 20437020), and the National Key Technologies R&D Program (2002A906A28-2).
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Communication
Interfacing Capillary Electrophoresis and Electrothermal Atomic Absorption Spectroscopy To Study Metal Speciation and Metal–Biomolecule Interactions†
Article first published online: 15 SEP 2005
DOI: 10.1002/anie.200501245
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Li, Y., Yan, X.-P. and Jiang, Y. (2005), Interfacing Capillary Electrophoresis and Electrothermal Atomic Absorption Spectroscopy To Study Metal Speciation and Metal–Biomolecule Interactions. Angew. Chem. Int. Ed., 44: 6387–6391. doi: 10.1002/anie.200501245
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Publication History
- Issue published online: 30 SEP 2005
- Article first published online: 15 SEP 2005
- Manuscript Received: 9 APR 2005
Keywords:
- analytical methods;
- atomic absorption spectroscopy;
- electrophoresis;
- metal speciation;
- metallomics
Happy couples: A new hybrid technique, capillary electrophoresis combined with online detection through electrothermal atomic absorption spectroscopy, allows the study of metal speciation and metal–biomolecule interactions, important aspects of metallomics. Advantages include complete sample introduction, nanoliter sample and reagent consumption, real-time detection, high sensitivity, and low cost.