Financial support from the National Natural Science Foundation of China, the Chinese Academy of Sciences, the Major Basic Research Development Program of China (Grant no. G2000077506), and the Ministry of Science and Technology of Shanghai Municipality is gratefully acknowledged. Binol=2,2′-dihydroxy-1,1′-binaphthyl.
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Communication
Heterogenization of Shibasaki's Binol/La Catalyst for Enantioselective Epoxidation of α,β-Unsaturated Ketones with Multitopic Binol Ligands: The Impact of Bridging Spacers†
Article first published online: 15 SEP 2005
DOI: 10.1002/anie.200501676
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Wang, X., Shi, L., Li, M. and Ding, K. (2005), Heterogenization of Shibasaki's Binol/La Catalyst for Enantioselective Epoxidation of α,β-Unsaturated Ketones with Multitopic Binol Ligands: The Impact of Bridging Spacers. Angew. Chem. Int. Ed., 44: 6362–6366. doi: 10.1002/anie.200501676
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Publication History
- Issue published online: 30 SEP 2005
- Article first published online: 15 SEP 2005
- Manuscript Received: 16 MAY 2005
Keywords:
- asymmetric catalysis;
- epoxidation;
- heterogeneous catalysis;
- ketones;
- lanthanum
Bridging the gap: Heterogenized Shibasaki's binol/La catalyst is synthesized by a self-supporting strategy through the reactions of multitopic ligands with La(OiPr)3 (see picture). The catalyst shows high activity and enantioselectivity, and can be reused in the asymmetric epoxidation of α,β-unsaturated ketones.