Versatile Hypervalent-Iodine(III)-Catalyzed Oxidations with m-Chloroperbenzoic Acid as a Cooxidant


  • This work was financially supported by a Grant-in-Aid for Scientific Research (S) from the Ministry of Education, Science, Sports and Culture (Japan).


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A new and effective use of hypervalent iodine(III) reagents as catalysts involves the transformation of iodoarenes 1 into hypervalent iodine(III) species 2 with meta-chloroperbenzoic acid (mCPBA) as the appropriate cooxidant. With observed turnover numbers greater than 70, this procedure paves the way for broader application of these useful oxidants in organic synthesis.