This material is based upon work supported by the U. S. Army Research Laboratory and the U. S. Army Research Office under grant number DAAD19-03-1-0227, and the U. S. National Science Foundation under grant number DMR-0117792.
Communication
Proofreading and Error Removal in a Nanomaterial Assembly†
Article first published online: 17 OCT 2005
DOI: 10.1002/anie.200501815
Copyright © 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Issue

Angewandte Chemie International Edition
Volume 44, Issue 44, pages 7290–7293, November 11, 2005
Additional Information
How to Cite
Liu, J., Wernette, D. P. and Lu, Y. (2005), Proofreading and Error Removal in a Nanomaterial Assembly. Angewandte Chemie International Edition, 44: 7290–7293. doi: 10.1002/anie.200501815
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Publication History
- Issue published online: 8 NOV 2005
- Article first published online: 17 OCT 2005
- Manuscript Received: 25 MAY 2005
- Abstract
- Article
- References
- Cited By
Keywords:
- DNA;
- enzymes;
- gold;
- materials science;
- nanotechnology
Graphical Abstract

We all make mistakes! The specific removal of error particles in nanomaterial assemblies is achieved by using a DNAzyme as a proofreading and error-removal unit (see picture of a DNA-templated gold nanoparticle assembly). Parallels can be drawn with the proofreading and error-removal process in biology. A and B=gold nanoparticles attached to DNA sequences; B′=error particle.

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