Communication

Highly Enantioselective sec-Alkyl Sulfatase Activity of the Marine Planctomycete Rhodopirellula baltica Shows Retention of Configuration†

  1. Sabine R. Wallner Dr.1,
  2. Marga Bauer Dr.2,
  3. Chris Würdemann2,
  4. Patricia Wecker2,
  5. Frank O. Glöckner Dr.2,
  6. Kurt Faber Prof.1

Article first published online: 14 SEP 2005

DOI: 10.1002/anie.200501955

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 44, Issue 39, pages 6381–6384, October 7, 2005

Additional Information

How to Cite

Wallner, S. R., Bauer, M., Würdemann, C., Wecker, P., Glöckner, F. O. and Faber, K. (2005), Highly Enantioselective sec-Alkyl Sulfatase Activity of the Marine Planctomycete Rhodopirellula baltica Shows Retention of Configuration. Angew. Chem. Int. Ed., 44: 6381–6384. doi: 10.1002/anie.200501955

Author Information

  1. 1

    Research Centre for Applied Biocatalysis, Department of Chemistry, Organic and Bioorganic Chemistry, University of Graz, Heinrichstrasse 28, 8010 Graz, Austria, Fax: (+43) 316-380-9840

  2. 2

    MPI Marine Microbiology, Celsiusstrasse 1, 28359 Bremen, Germany

  1. †

    This study was performed within the Research Centre for Applied Biocatalysis. Financial support by the FFG, the City of Graz, and the Province of Styria is gratefully acknowledged. L. Arbanas, T. Glieder, W. Kroutil, and U. Wagner (Graz) are thanked for their valuable contributions in sequence analysis.

Publication History

  1. Issue published online: 30 SEP 2005
  2. Article first published online: 14 SEP 2005
  3. Manuscript Received: 6 JUN 2005

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Keywords:

  • enantioselectivity;
  • hydrolysis;
  • stereoselectivity;
  • sulfatases;
  • sulfate esters
Thumbnail image of graphical abstract

Hydrolytic enzymes: The marine planctomycete Rhodopirellula baltica DSM 10527 displays high stereo- and enantioselective alkyl sulfatase activity towards (±)-sec-alkyl sulfates with retention of configuration through cleavage of their S[BOND]O bond (see scheme; pathway B), whereas inversion of configuration is observed upon cleavage of the C[BOND]O bond (pathway A).

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