Communication

One-Pot Reaction Cascades Using Star Polymers with Core-Confined Catalysts†

  1. Brett Helms2,
  2. Steven J. Guillaudeu2,
  3. Yu Xie2,
  4. Meredith McMurdo2,
  5. Craig J. Hawker Prof.1,
  6. Jean M. J. Fréchet Prof.2

Article first published online: 14 SEP 2005

DOI: 10.1002/anie.200502095

Issue

Angewandte Chemie International Edition

Angewandte Chemie International Edition

Volume 44, Issue 39, pages 6384–6387, October 7, 2005

Additional Information

How to Cite

Helms, B., Guillaudeu, S. J., Xie, Y., McMurdo, M., Hawker, C. J. and Fréchet, J. M. J. (2005), One-Pot Reaction Cascades Using Star Polymers with Core-Confined Catalysts. Angew. Chem. Int. Ed., 44: 6384–6387. doi: 10.1002/anie.200502095

Author Information

  1. 1

    Materials Research Laboratory, University of California, Santa Barbara, CA 93106, USA, Fax: (+1) 805-893-8797

  2. 2

    Department of Chemistry, University of California, Berkeley, CA 94720, USA, Fax: (+1) 510-643-3079

  1. †

    This work was funded through the National Science Foundation (NSF-DMR0317514) and the Department of Energy (DE-AC03-76SF00098). Dr. Jeffrey Pyun contributed to early exploratory work on this project.

Publication History

  1. Issue published online: 30 SEP 2005
  2. Article first published online: 14 SEP 2005
  3. Manuscript Received: 16 JUN 2005

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (125K)

Keywords:

  • amines;
  • dendrimers;
  • homogeneous catalysis;
  • polymers;
  • reaction cascades
Thumbnail image of graphical abstract

My stars! Star polymers that contain otherwise incompatible acid or base catalysts, such as para-toluenesulfonic acid or 4-(dialkylamino)pyridines moieties, at their sterically restricted cores (see scheme) are readily prepared. Homogeneous catalysis using these star polymers can perform reaction cascades in the same pot and is demonstrated with an acid-catalyzed deprotection and the nucleophilic amine-catalyzed Baylis–Hillman reaction.

View Full Article (HTML) Get PDF (125K)